Lodge 49 is an American comedy-drama television series created by Jim Gavin. It aired on the cable television network AMC in the United States from August 6, 2018, to October 14, 2019, spanning two seasons and 20 episodes. The title alludes to the novella The Crying of Lot 49 by Thomas Pynchon, which Gavin references as an inspiration. Although the series was met with positive reviews, AMC canceled the series after its second season due to low ratings.

The Crying of Lot 49 is a 1966 novella by the American author Thomas Pynchon. The shortest of Pynchon's novels, the plot follows Oedipa Maas, a young Californian woman who begins to embrace a conspiracy theory as she possibly unearths a centuries-old feud between two mail distribution companies. One of these companies, Thurn and Taxis, actually existed, operating from 1490–1990, and was the first private firm to distribute postal mail. Like most of Pynchon's writing, The Crying of Lot 49 is often described as postmodernist literature. Time included the novel in its "TIME 100 Best English-Language Novels from 1923 to 2005".