Lok Ma Chau is the northwestern terminus in Lok Ma Chau on the Lok Ma Chau Spur Line, a branch line of the East Rail line of Hong Kong's MTR network, which was built to alleviate the immigration checkpoint between Hong Kong and mainland China's Shenzhen at Lo Wu station. MTR Corporation promotes use of Lok Ma Chau as a direct connection with Line 4 of the Shenzhen Metro, which is also operated by the MTR Corporation alongside Line 10.

The East Rail line is one of the ten lines that form MTR, the mass transit system in Hong Kong. The railway line starts at Lo Wu or Lok Ma Chau, both of which are boundary crossing points into Shenzhen and joins in the north at Sheung Shui and ends at Admiralty station on Hong Kong Island. At approximately 46 km (29 mi), the line is the second longest line within the network, behind the Tuen Ma line. The line's colour is light blue, formerly navy blue before the KCR/MTR merger.