The Lomonosov Gold Medal, named after Russian scientist and polymath Mikhail Lomonosov, is awarded each year since 1959 for outstanding achievements in the natural sciences and the humanities by the USSR Academy of Sciences and later the Russian Academy of Sciences (RAS). Since 1967, two medals are awarded annually: one to a Russian and one to a foreign scientist. It is the academy's highest accolade.

Mikhail Vasilyevich Lomonosov was a Russian polymath, scientist and writer, who made important contributions to literature, education, and science. Among his discoveries were the atmosphere of Venus and the law of conservation of mass in chemical reactions. His spheres of science were natural science, chemistry, physics, mineralogy, history, art, philology, optical devices and others. The founder of modern geology, Lomonosov was also a poet and influenced the formation of the modern Russian literary language.