London Buses route 135 is a Transport for London contracted bus route in London, England. Running between Cubitt Town and Moorfields Eye Hospital, it is operated by Stagecoach London.

Cubitt Town is a district on the eastern side of the Isle of Dogs in London, England. This part of the former Metropolitan Borough of Poplar was redeveloped as part of the Port of London in the 1840s and 1850s by William Cubitt, Lord Mayor of London (1860–1862), after whom it is named. It is on the east of the Isle, facing the Royal Borough of Greenwich across the River Thames. To the west is Millwall, to the east and south is Greenwich, to the northwest Canary Wharf, and to the north — across the Blue Bridge — is Blackwall. The district is situated within the Blackwall & Cubitt Town Ward of Tower Hamlets London Borough Council.