The Lord & Taylor Building is an 11-story commercial building in Midtown Manhattan, New York City, that formerly served as Lord & Taylor's flagship department store in the city. Designed by Starrett & van Vleck in the Italian Renaissance Revival style, it is at 424–434 Fifth Avenue between 38th and 39th Streets. Since 2023, it has been an office building for Amazon.

Lord & Taylor was the oldest-surviving department store chain in the United States. The company operated full-line department stores from 1826 until it filed for bankruptcy in 2020. The following year, in 2021, it closed all its brick-and-mortar stores. Saadia Group acquired the Lord & Taylor intellectual property and relaunched the e-commerce website later that same year.