Loretto is a borough in Cambria County, Pennsylvania, United States. As of the 2010 census it had a population of 1,302. Like the rest of Cambria County, it is part of the Johnstown, Pennsylvania, Metropolitan Statistical Area. Loretto is the home of Saint Francis University.

Cambria County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 133,472. Its county seat is Ebensburg. The county was created on March 26, 1804, from parts of Bedford, Huntingdon, and Somerset counties and later organized in 1807. It was named for the nation of Wales, which in Latin is known as "Cambria". The county is part of the Southwest Pennsylvania region of the state.