Lori Grimes is a fictional character from the comic book series The Walking Dead and was portrayed by Sarah Wayne Callies in the American television series of the same name. Created by writer Robert Kirkman and artist Tony Moore, the character made her debut in The Walking Dead #2 in 2003. In both forms of media, she is married to Rick Grimes. They have two children Carl and Judith. The character escapes the zombie apocalypse with Carl, and Rick's partner Shane Walsh. Believing her husband to be dead, she starts a relationship with Shane. But then she finds her husband is alive and breaks it off with Shane.

The Walking Dead is an American post-apocalyptic comic book series created by writer Robert Kirkman and artist Tony Moore – who was the artist on the first six issues and cover artist for the first twenty-four – with art on the remainder of the series by Charlie Adlard. Beginning in 2003 and published by Image Comics, the series ran for 193 issues, with Kirkman unexpectedly ending the series in 2019. Apart from a few specials, the comic was published primarily in black and white. It began publishing colorized versions issue by issue, colored by Dave McCaig, starting in October 2020.