Los Feliz is a hillside neighborhood in the greater Hollywood area of Los Angeles, California, abutting Hollywood and encompassing part of the Santa Monica Mountains. The neighborhood is named after the Feliz family of Californios who had owned the area since 1795, when José Vicente Féliz was granted Rancho Los Feliz.

U.S. Route 101 (US 101) is a major north–south United States Numbered Highway, stretching from Los Angeles, California, to Tumwater, Washington. The California portion of US 101 is one of the last remaining and longest U.S. Routes still active in the state, and the longest highway of any kind in California. US 101 was also one of the original national routes established in 1926. Significant portions of US 101 between the Los Angeles area and the San Francisco Bay Area follow El Camino Real, the commemorative route connecting the former Alta California's 21 missions.