Loudon County is a county in the U.S. state of Tennessee. It is located in the central part of East Tennessee. As of the 2020 census, the population was 54,886. Its county seat is Loudon. Loudon County is included in the Knoxville, TN Metropolitan Statistical Area.

Knoxville is a city in and the county seat of Knox County, Tennessee, United States. As of the 2020 United States census, Knoxville's population was 190,740, making it the largest city in the East Tennessee Grand Division and the state's third-most-populous city after Nashville and Memphis. It is the principal city of the Knoxville metropolitan area, which had a population of 879,773 in 2020.