Louis Capone was a New York organized crime figure who became a supervisor for Murder, Inc. Louis Capone was not related to Al Capone, the boss of the Chicago Outfit. Capone was convicted of murder in 1941, and sentenced to death. He was electrocuted at Sing Sing Prison on March 4, 1944.

Murder, Inc. was an organized crime group active from 1929 to 1941 that acted as the enforcement arm of the National Crime Syndicate – a closely connected criminal organization that included the Italian-American Mafia, the Jewish Mob, and other criminal organizations in New York City and elsewhere. Murder, Inc. was composed of Jewish and Italian-American gangsters, and members were mainly recruited from poor and working-class Jewish and Italian neighborhoods in Manhattan and Brooklyn. It was initially headed by Louis "Lepke" Buchalter and later by Albert "Mad Hatter" Anastasia.