Louis McLane was an American lawyer and politician from Wilmington, in New Castle County, Delaware, and Baltimore, Maryland. He was a veteran of the War of 1812, a member of the Federalist Party and later the Democratic Party. He served as the U.S. representative from Delaware, U.S. senator from Delaware, the tenth U.S. Secretary of the Treasury, the twelfth U.S. Secretary of State, ambassador to Great Britain, and president of the Baltimore and Ohio Railroad.

The Federalist Party was a conservative and nationalist American political party and the first political party in the United States. It dominated the national government under Alexander Hamilton from 1789 to 1801. The party was defeated by the Democratic-Republican Party in 1800, and it became a minority party while keeping its stronghold in New England. It made a brief resurgence by opposing the War of 1812, then collapsed with its last presidential candidate in 1816. Remnants lasted for a few years afterwards.