Louisiana Highway 21 is a state highway in Louisiana that serves St. Tammany and Washington Parishes. It spans 51.76 miles and is signed north and south.
Improved, multilane, divided section of LA 21 between Covington and Madisonville
Louisiana Highway 59 is a state highway located in St. Tammany Parish, Louisiana. It runs 11.74 miles in a north–south direction from U.S. Highway 190 in Mandeville to LA 21 north of Abita Springs.
Signage on the eastbound I-12 ramp to LA 59 directs travelers confusing the route with I-59, located about 20 miles (32 km) farther east, to get back onto I-12 eastbound.