Loxley is a city in Baldwin County, Alabama, United States. As of the 2010 census, the population of the town was 1,632. It is part of the Daphne-Fairhope-Foley metropolitan area. Loxley is becoming a popular location for the expansion of the suburbs from Daphne and Spanish Fort, Alabama, because it is served by an Interstate 10 exit and is almost directly between the cities of Mobile, Alabama, and Pensacola, Florida.

Baldwin County is a county located in the southwestern part of the U.S. state of Alabama, on the Gulf coast. It is one of only two counties in Alabama that border the Gulf of Mexico, along with Mobile County. As of the 2020 census, the population was 231,767, making it the fourth-most populous county in Alabama. The county seat is Bay Minette. The county is named after the founder of the University of Georgia, Senator Abraham Baldwin.