Lucas Tyree Kunce is an American attorney and politician who is the director of national security at the American Economic Liberties Project. On March 9, 2021, he announced his campaign for the 2022 U.S. Senate election in Missouri, the day after Roy Blunt announced his retirement. He lost the Democratic primary to Trudy Busch Valentine. On January 6, 2023, he announced his campaign to run for Missouri's Class 1 U.S. Senate seat in 2024 against incumbent Josh Hawley.

The 2022 United States Senate election in Missouri was held on November 8, 2022, concurrently with elections for all other Class 3 U.S. senators and elections for the U.S. House of Representatives, to select a member of the United States Senate to represent the state of Missouri. Incumbent senator Roy Blunt, a Republican, did not seek a third term in office. Republican Missouri Attorney General Eric Schmitt won the open seat, defeating Democrat Trudy Busch Valentine.