The Ludwigshafen (Rhein) Mitte station is in the southern part of the centre of the city of Ludwigshafen am Rhein in the German state of Rhineland-Palatinate. It was established in 2003 and is classified by Deutsche Bahn as a category 4 station.

Ludwigshafen, officially Ludwigshafen am Rhein, is a city in the German state of Rhineland-Palatinate, on the river Rhine, opposite Mannheim. With Mannheim, Heidelberg, and the surrounding region, it forms the Rhine Neckar Area.