Luis de Velasco y Ruiz de Alarcón was the second viceroy of New Spain during the Spanish colonization of the Americas in the mid-sixteenth century.

Luis de Velasco, 1st Marquess of Salinas del Río Pisuerga was a Spanish nobleman who was the ninth viceroy of New Spain from January 27, 1590 to November 4, 1595, and again from July 2, 1607, to June 10, 1611. In between he was viceroy of Peru for eight years, from July 24, 1596, to January 18, 1604. He was known as Luis de Velasco, hijo to distinguish him from his father, Luis de Velasco, the second viceroy of New Spain.