Lushoto is one of the eleven districts of Tanga Region in Tanzania. It is bordered to the northeast by Kenya, to the east by the Muheza District, to the northwest by the Kilimanjaro Region, west by Korogwe District and to the south by the Bumbuli District. The district's capital and largest town is Lushoto.

The Usambara Mountains of northeastern Tanzania in tropical East Africa, comprise the easternmost ranges of the Eastern Arc Mountains. The ranges of approximately 90 kilometres (56 mi) long and about half that wide, are situated in the Lushoto District of the Tanga Region. They were formed nearly two million years ago by faulting and uplifting, and are composed of Precambrian metamorphic rocks. They are split into two sub-ranges; the West Usambaras being higher than the East Usambaras, which are nearer the coast and receive more rainfall.