Lygosominae is the largest subfamily of skinks in the family Scincidae. The subfamily can be divided into a number of genus groups. If the rarely used taxonomic rank of infrafamily is employed, the genus groups would be designated as such, but such a move would require a formal description according to the ICZN standards.

Skinks are lizards belonging to the family Scincidae, a family in the infraorder Scincomorpha. With more than 1,500 described species across 100 different taxonomic genera, the family Scincidae is one of the most diverse families of lizards. Skinks are characterized by their smaller legs in comparison to typical lizards and are found in different habitats except arctic and subarctic regions.