Lymph node stromal cell
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Lymph node stromal cells are essential to the structure and function of the lymph node whose functions include: creating an internal tissue scaffold for the support of hematopoietic cells; the release
Diagram of a lymph node.
Histological section of a normal lymph node
Lymphocyte surrounded by red blood cells.
Follicular dendritic cells
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Follicular dendritic cells are cells of the immune system found in primary and secondary lymph follicles of the B cell areas of the lymphoid tissue. Unlike dendritic cells, FDCs are not derived from t
This is an isolated Follicular Dendritic Cell cultured on collagen. It shows a cell body and numerous dendritic cell processes interdigitating with one another and with dendrites of adjacent FDCs to form a network. This network traps antigen in the form of immune complexes and helps initiate an antibody response by B cells
Histologic comparison of cell types in a germinal center, H&E stain: - Centrocytes are small to medium size with angulated, elongated, cleaved, or twisted nuclei. - Centroblasts are larger cells containing vesicular nuclei with one to three basophilic nucleoli apposing the nuclear membrane. - Follicular dendritic cells have round nuclei, centrally located nucleoli, bland and dispersed chromatin, and flattening of adjacent nuclear membrane.