The Mütter Museum is a medical history and science museum located in the Center City area of Philadelphia, Pennsylvania. It contains a collection of anatomical and pathological specimens, wax models, and antique medical equipment. The museum is part of The College of Physicians of Philadelphia. The original purpose of the museum, founded with a gift from Dr. Thomas Dent Mütter on December 11, 1858, was for the education of medical professionals, medical students, and invited guests of College Fellows, and did not become open to non-Fellows until the mid-1970s. The College of Physicians of Philadelphia is itself not a teaching organization, but rather a member organization or "scientific body dedicated to the advancement of science and medicine".

Center City includes the central business district and central neighborhoods of Philadelphia, Pennsylvania, United States. It comprises the area that made up the City of Philadelphia prior to the Act of Consolidation, 1854, which extended the city borders to be coterminous with Philadelphia County.