MSC Virtuosa is a Meraviglia-Plus-class cruise ship owned and operated by MSC Cruises. Built by Chantiers de l'Atlantique in Saint-Nazaire, France, she is the second ship in the Meraviglia-Plus class and sister ship to MSC Grandiosa. Originally scheduled to debut on 8 November 2020, her delivery and entry into service was delayed due to the COVID-19 pandemic. She was delivered to MSC Cruises on 1 February 2021 and entered service in May 2021.

MSC Cruises is a Swiss-Italian global cruise line based in Geneva, with operations offices in Naples, Genoa and Venice. It was founded in 1970 in Naples, Italy, as part of the Mediterranean Shipping Company (MSC). In addition to being the world's largest privately held cruise company, employing about 23,500 people worldwide and with offices in 45 countries as of 2017, MSC Cruises is the third-largest cruise company in the world, after Carnival Corporation & plc and Royal Caribbean Group, with a 10.2% share of all passengers carried in 2021.