The Macau Grand Prix is an annual motorsport road racing event for automobiles and motorcycles held on the Guia Circuit in Macau. The event includes the Formula 3 Macau Grand Prix and Macau Motorcycle Grand Prix title races, with other races for touring, grand touring, sports and Formula 4 cars.

The Guia Circuit, or Circuito da Guia, is a 6.120 km (3.803 mi) street circuit located at the southeast region of the Macau Peninsula in Macau. It is the venue of the Macau Grand Prix and Guia Race of Macau. The circuit consists of long straights and tight corners, and features the characteristics of a typical street circuit - narrow, bumpy and limited overtaking opportunities. However, there are two special features that can rarely be found in other street circuits - variation in altitude and an ultra long main straight that allows top speed of 260 km/h (160 mph) on Formula Three cars. As a result, the circuit is recognised as one of the most challenging circuits in the world in terms of both driving and tuning, as cars have to maintain competitive speed to overcome hill-climbing, twisty corners and long straights in a single lap.