Macclesfield Sunday School is in Roe Street, Macclesfield, Cheshire, England. It started in 1796 as a non-denominational Sunday School in Pickford Street, which catered for 40 children. It was founded by John Whitaker whose objective was "to lessen the sum of human wretchedness by diffusing religious knowledge and useful learning among the lower classes of society". Though chapels set up their denominational schools, the Sunday School committee in 1812 elected to erect a purpose-built school on Roe Street. The Big Sunday School had 1,127 boys and 1,324 girls on its books when it opened. The building is now known as The Old Sunday School and is part of Macclesfield Museums.

Macclesfield is a market town and civil parish in the unitary authority of Cheshire East, Cheshire, England, on the River Bollin and the edge of the Cheshire Plain, with Macclesfield Forest to its east, 16 miles (26 km) south of Manchester and 38 miles (61 km) east of Chester.