Madisonburg is an unincorporated community and census-designated place (CDP) in Miles Township, Centre County, Pennsylvania, United States. It is part of the State College, Pennsylvania Metropolitan Statistical Area. The population was 168 at the 2010 census.

Pennsylvania Route 192 is a state highway located in central Pennsylvania. The western terminus of the route is at PA 144 in Centre Hall. The eastern terminus is at U.S. Route 15 in Lewisburg.