Mahidol University is an autonomous public research university in Thailand. The university was founded as part of Siriraj Hospital in 1888. It was first called the University of Medical Science in 1943, and has been recognized as Thailand's fourth public university. The university was renamed in 1969 by King Bhumibol Adulyadej for his father, Prince Mahidol of Songkhla, known as the "Father of Modern Medicine and Public Health in Thailand".

Mahitala Dhibesra Adulyadej Vikrom, the Prince Father, formerly Prince Mahidol Adulyadej, Prince of Songkla or Mahidol Songkla, was the father of King Ananda Mahidol and King Bhumibol Adulyadej of Thailand, and the paternal grandfather of King Vajiralongkorn. He was also regarded as the father of modern medicine and public health in Thailand. He also founded the House of Mahidol or the present Royal Family of Thailand. His two sons reigned for more than eight decades, longer than the Ibn Saud siblings of Saudi Arabia, and the Nahyan siblings of Abu Dhabi.