The Main Line of Public Works was a package of legislation passed by the Commonwealth of Pennsylvania in 1826 to establish a means of transporting freight between Philadelphia and Pittsburgh. It funded the construction of various long-proposed canal and road projects, mostly in southern Pennsylvania, that became a canal system and later added railroads. Built between 1826 and 1834, it established the Pennsylvania Canal System and the Allegheny Portage Railroad.

The Delaware Division of the Pennsylvania Canal, more commonly called the Delaware Canal, runs for 60 miles (97 km) parallel to the right bank of the Delaware River from the entry locks near the mouth of the Lehigh River and terminal end of the Lehigh Canal at Easton south to Bristol. At Easton, which today is the home of The National Canal Museum, the Delaware Canal also connected with the Morris Canal built to carry anthracite coal to energy-starved New Jersey industries.