Main Street is the most important commercial street in Salt Lake City, Utah, United States though it also extends south into the cities of South Salt Lake, Millcreek, and Murray. Its commercial importance is almost totally derived from the few blocks of the street which are immediately south of Temple Square that have attracted banks, major retailers, and heavy foot traffic throughout Salt Lake City's history; the long southern extension of Main Street south of about 500 and 600 South, in contrast, is always in the shadow of State Street, which is more designed for the long-distance automobile traffic that is common away from downtown.

Salt Lake City, often shortened to Salt Lake or SLC, is the capital and most populous city of the U.S. state of Utah. It is the seat of Salt Lake County, the most populous county in the state. The city is the core of the Salt Lake City Metropolitan Statistical Area (MSA), which had a population of 1,257,936 at the 2020 census. Salt Lake City is further situated within a larger metropolis known as the Salt Lake City–Ogden–Provo Combined Statistical Area, a corridor of contiguous urban and suburban development stretched along a 120-mile (190 km) segment of the Wasatch Front, comprising a population of 2,746,164, making it the 22nd largest in the nation. With a population of 200,133 in 2020, it is the 117th most populous city in the United States. It is also the central core of the larger of only two major urban areas located within the Great Basin.