The Main Street District of downtown Dallas, Texas runs along Main Street and is bounded by Elm Street one block north, Commerce St. one block south, N. Lamar St. to the west, and US 75/I-45 (I-345) elevated highway to the east. The district is the spine of downtown Dallas, and connects many of the adjoining business and entertainment districts. It does not include Dealey Plaza or the John Fitzgerald Kennedy Memorial which are a few blocks west in the West End Historic District.

Downtown Dallas is the central business district (CBD) of Dallas, Texas, United States, located in the geographic center of the city. It is the second-largest business district in the state of Texas. The area termed "Downtown" has traditionally been defined as bounded by the downtown freeway loop, bounded on the east by I-345 (although known and signed as the northern terminus of I-45 and the southern terminus of US 75, on the west by I-35E, on the south by I-30, and on the north by Woodall Rodgers Freeway.