Makarand Deshpande is an Indian actor, writer, and director in Hindi, Kannada, Marathi, Telugu, Malayalam, Tamil cinema, and Indian theatre. He is often seen in supporting and pivotal roles in films like Jungle, Sarfarosh, Swades, Makdee, Satya,Bbuddah... Hoga Terra Baap and Darna Zaroori Hai where he plays drunkard, wayfarer, and comic roles. He has directed five films.

Makdee, promoted as The Web Of The Witch, in English, is a 2002 Indian comedy horror film written and directed by Vishal Bhardwaj. It stars Shabana Azmi, Makrand Deshpande, Shweta Basu Prasad and Alaap Mazgaonkar. The film tells the story of a young girl in north India and her encounter with an alleged witch in an old mansion in the locality, believed by the locals to be haunted. It also explains the belief in witches and witchcraft across modern day India. The film was screened in the Critics' Week section at the 2003 Cannes Film Festival.