Makeni is the largest city in the Northern Province of Sierra Leone. The city is the capital of Bombali District, and is the economic center of the Northern Province. Makeni is the fifth largest city in Sierra Leone by population. The city of Makeni had a population of 85,116 in the 2021 census. Makeni lies approximately 110 miles east of Freetown. Makeni is home to the University of Makeni, the largest private university in Sierra Leone.

The First Responder Coalition of Sierra Leone (FRCSL) is a coalition of Sierra Leonean and international organizations dedicated to expanding prehospital emergency care and developing emergency medical services in Sierra Leone. It aims to address the high rates of injury and low rates of prehospital emergency care available in the country.