Mary Anne "Mamie" Cadden was an American-born Irish midwife, backstreet abortionist, and convicted murderer. She was born 27 October 1891 in Scranton, Pennsylvania, to Irish parents Patrick and Mary Cadden. In 1895, Cadden and her family returned to Lahardane in County Mayo, Ireland, where she completed years of schooling. Once she obtained her spot on the list of licensed midwives in Dublin, she opened a series of maternity nursing homes to aid women with health issues and to perform illegal abortions. After a series of criminal convictions, Cadden lost her status as a licensed midwife. In 1944, Cadden was charged and convicted for the murder of 33-year-old Helen O'Reilly. She was sentenced to life in prison, and after a year at Mountjoy prison, she was declared insane and moved to the criminal lunatic asylum Dundrum, where she died of a heart attack on 20 April 1959. Although many people committed backstreet abortions during the period of Cadden's life, Cadden was the only person in Ireland to be sentenced to the death penalty for a maternal death occurring as a result of an abortion. As the most notorious Irish abortionist of her era, the term 'Nurse Cadden' was synonymous with evil in the Irish public's mind.

Hume Street is a street in central Dublin located between Ely Place and St. Stephen's Green. It is named after Sir Gustavus Hume, 3rd Baronet (c.1670–1731) and his family.