Mamluk architecture was the architectural style that developed under the Mamluk Sultanate (1250–1517), which ruled over Egypt, the Levant, and the Hijaz from their capital, Cairo. Despite their often tumultuous internal politics, the Mamluk sultans were prolific patrons of architecture and contributed enormously to the fabric of historic Cairo. The Mamluk period, particularly in the 14th century, oversaw the peak of Cairo's power and prosperity. Their architecture also appears in cities such as Damascus, Jerusalem, Aleppo, Tripoli, and Medina.

Sultan Abu Al-Nasr Sayf ad-Din Al-Ashraf Qaitbay was the eighteenth Burji Mamluk Sultan of Egypt from 872 to 901 A.H.. He was Circassian by birth, and was purchased by the ninth sultan Barsbay before being freed by the eleventh Sultan Jaqmaq. During his reign, he stabilized the Mamluk state and economy, consolidated the northern boundaries of the Sultanate with the Ottoman Empire, engaged in trade with other contemporaneous polities, and emerged as a great patron of art and architecture. In fact, although Qaitbay fought sixteen military campaigns, he is best remembered for the spectacular building projects that he sponsored, leaving his mark as an architectural patron on Mecca, Medina, Jerusalem, Damascus, Aleppo, Alexandria, and every quarter of Cairo.