Manaus is the capital and largest city of the Brazilian state of Amazonas. It is the seventh-largest city in Brazil, with an estimated 2020 population of 2,219,580 distributed over a land area of about 11,401 km2 (4,402 sq mi). Located at the east centre of the state, the city is the centre of the Manaus metropolitan area and the largest metropolitan area in the North Region of Brazil by urban landmass. It is situated near the confluence of the Negro and Amazon rivers. It is one of the two cities in the Amazon Rainforest with a population of over 1 million people, alongside Belém.

Amazonas is a state of Brazil, located in the North Region in the north-western corner of the country. It is the largest Brazilian state by area and the ninth-largest country subdivision in the world. It is the largest country subdivision in South America, being greater than the areas of Chile, Paraguay, and Uruguay combined. Mostly located in the Southern Hemisphere, Amazonas is the third-largest country subdivision in the Southern Hemisphere after the Australian states of Western Australia and Queensland. Located entirely in the Western Hemisphere, it is the fourth-largest country subdivision in the Western Hemisphere after Greenland, Nunavut, and Alaska. If independent, Amazonas could become the sixteenth-largest country in the world, slightly larger than Mongolia. Neighbouring states are Roraima, Pará, Mato Grosso, Rondônia, and Acre. It also borders the nations of Peru, Colombia and Venezuela. This includes the Departments of Amazonas, Vaupés and Guainía in Colombia, as well as the Amazonas state in Venezuela, and the Loreto Region in Peru.