The Manhattan–Junction City Combined Statistical Area, as defined by the United States Census Bureau, is an area consisting of three counties in northeastern Kansas, anchored by the city of Manhattan. It was upgraded from a Micropolitan Statistical Area (μSA) to a Metropolitan Statistical Area (MSA) by the Office of Management and Budget on November 20, 2008. It was changed from a Metropolitan Statistical Area (MSA) to a Combined Statistical Area (CSA) by the Office of Management and Budget on February 28, 2013.

Manhattan is a city in and the county seat of Riley County, Kansas, U.S., although the city extends into Pottawatomie County. It is located in northeastern Kansas at the junction of the Kansas River and Big Blue River. As of the 2020 Census, the population of the city was 54,100.