Manoa is a valley and a residential neighborhood of Honolulu, Hawaiʻi. The neighborhood is approximately three miles east and inland from downtown Honolulu and less than a mile from Ala Moana and Waikiki.

The University of Hawaiʻi at Mānoa is a public land-grant research university in Mānoa, a neighborhood of Honolulu, Hawaii. It is the flagship campus of the University of Hawaiʻi system and houses the main offices of the system. Most of the campus occupies the eastern half of the mouth of Mānoa Valley, with the John A. Burns School of Medicine located adjacent to the Kakaʻako Waterfront Park.