Manual scavenging is a term used mainly in India for "manually cleaning, carrying, disposing of, or otherwise handling, human excreta in an insanitary latrine or in an open drain or sewer or in a septic tank or a pit". Manual scavengers usually use hand tools such as buckets, brooms and shovels. The workers have to move the excreta, using brooms and tin plates, into baskets, which they carry to disposal locations sometimes several kilometers away. The practice of employing human labour for cleaning of sewers and septic tanks is also prevalent in Bangladesh and Pakistan. These sanitation workers, called "manual scavengers", rarely have any personal protective equipment. The work is regarded as a dehumanizing practice.

A sanitation worker is a person responsible for cleaning, maintaining, operating, or emptying the equipment or technology at any step of the sanitation chain. This is the definition used in the narrower sense within the WASH sector. More broadly speaking, sanitation workers may also be involved in cleaning streets, parks, public spaces, sewers, stormwater drains, and public toilets. Another definition is: "The moment an individual’s waste is outsourced to another, it becomes sanitation work." Some organizations use the term specifically for municipal solid waste collectors, whereas others exclude the workers involved in management of solid waste sector from its definition.