The Mapuche are a group of indigenous inhabitants of south-central Chile and southwestern Argentina, including parts of Patagonia. The collective term refers to a wide-ranging ethnicity composed of various groups who share a common social, religious, and economic structure, as well as a common linguistic heritage as Mapudungun speakers. Their homelands once extended from Choapa Valley to the Chiloé Archipelago and later spread eastward to Puelmapu, a land comprising part of the Argentine pampa and Patagonia. Today the collective group makes up over 80% of the indigenous peoples in Chile and about 9% of the total Chilean population. The Mapuche are concentrated in the Araucanía region. Many have migrated from rural areas to the cities of Santiago and Buenos Aires for economic opportunities, more than 92% of the Mapuches are from Chile.

The Tehuelche people, also called the Aónikenk, are an Indigenous people from eastern Patagonia in South America. In the 18th and 19th centuries the Tehuelche were influenced by Mapuche people, and many adopted a horseriding lifestyle. Once a nomadic people, the lands of the Tehuelche were colonized in the 19th century by Argentina and Chile, gradually disrupting their traditional economies. The establishment of large sheep farming estates in Patagonia was particularly detrimental to the Tehuelche. Contact with outsiders also brought in infectious diseases ushering deadly epidemics among Tehuelche tribes. Most existing members of the group currently reside in cities and towns of Argentine Patagonia.