Marcy-Holmes is a neighborhood in the University community of Minneapolis. The majority of the area is residential and sits upon a bluff overlooking the river and the city skyline. A small section of the neighborhood along the river is an industrial zone.

Minneapolis is officially defined by its city council as divided into 83 neighborhoods. The neighborhoods are historically grouped into 11 communities. Informally, there are city areas with colloquial labels. Residents may also group themselves by their city street suffixes: North, Northeast, South, and Southeast.