Margaret of Anjou was Queen of England by marriage to King Henry VI from 1445 to 1461 and again from 1470 to 1471. Through marriage, she was also nominally Queen of France from 1445 to 1453. Born in the Duchy of Lorraine into the House of Valois-Anjou, Margaret was the second eldest daughter of René, King of Naples, and Isabella, Duchess of Lorraine.

Richard of York, 3rd Duke of York, also named Richard Plantagenet, was a leading English magnate and claimant to the throne during the Wars of the Roses. He was a member of the ruling House of Plantagenet by virtue of being a direct male-line descendant of Edmund of Langley, King Edward III's fourth surviving son. However, it was through his mother, Anne Mortimer, a descendant of Edward III's second surviving son, Lionel of Antwerp, that Richard inherited his strongest claim to the throne, as the opposing House of Lancaster was descended from John of Gaunt, Duke of Lancaster, the third surviving son of Edward III. He also inherited vast estates and served in various offices of state in Ireland, France and England, a country he ultimately governed as Lord Protector due to the mental instability of King Henry VI.