Margo Hughes is a fictional character on the daytime soap opera As the World Turns, a show about working life in the fictional town of Oakdale. She was first played by Margaret Colin, and then by Hillary B. Smith for six years. However the actress most recognized for the role is Ellen Dolan, who played the character from December 18, 1989 until 2010, with a break from January 1993 to June 1994.

Margaret Colin is an American actress. She is known for her roles as Margo Hughes on As the World Turns and as Eleanor Waldorf-Rose on Gossip Girl.