Maria Full of Grace is a 2004 Spanish-language drama film written and directed by Joshua Marston. The film was is a US-Colombia co-production. The story follows a Colombian girl who becomes a drug mule for a trafficking ring. Lead actress Catalina Sandino Moreno was named Best Actress at the Berlin Film Festival, and was nominated for the Academy Award for Best Actress in the 77th Academy Awards.

Catalina Sandino Moreno is a Colombian actress. She shared the Silver Bear with Charlize Theron and received a nomination for the Academy Award for Best Actress for her leading role in Maria Full of Grace (2004). Since 2022, she has starred as Tabitha Matthews in the MGM+ television series From.