The Marianites of Holy Cross (MSC) is a Catholic congregation of nuns, founded in Le Mans, France, in 1841, by Fr Basil Moreau. It was founded as a third distinct society within the Congregation of Holy Cross. The Marianites of Holy Cross is now an independent congregation.

Basil Moreau, C.S.C. was the French priest who founded the Congregation of Holy Cross from which two additional congregations were founded, namely the Marianites of Holy Cross and the Sisters of the Holy Cross. Moreau was beatified on September 15, 2007 in Le Mans, France.