Marie Wilson was an American radio, film, and television actress. She may be best remembered as the title character in My Friend Irma.

My Friend Irma is a media franchise that was spawned by a top-rated, long-running radio situation comedy created by writer-director-producer Cy Howard. The radio show was so popular in the late 1940s that its success escalated the films, television, a comic strip and a comic book that comprise the franchise. Marie Wilson portrayed the title character Irma Peterson on radio, in two films and the television series. The radio series was broadcast on CBS from April 11, 1947, to August 23, 1954.