Marika Mitsotakis was the wife of the former Prime Minister of Greece Konstantinos Mitsotakis. She was regarded as a prominent political voice with the New Democracy political party, her husband's government, and Greek politics. She was nicknamed "Mrs. Marika" among Greeks.

Konstantinos Mitsotakis was a Greek politician who was Prime Minister of Greece from 1990 to 1993. He graduated in law and economics from the University of Athens. His son, Kyriakos Mitsotakis, was elected as the Prime Minister of Greece following the 2019 Greek legislative election.