Mark Keppel High School (MKHS) is a four-year California Distinguished School located in the city of Alhambra, California, in the Alhambra Unified School District. The school is on the southern edge of Alhambra, adjacent to the city of Monterey Park, and borders the Interstate 10 Freeway. Mark Keppel serves students from portions of Alhambra and Monterey Park. Mark Keppel has been accredited by the Western Association of Schools and Colleges in 1996, 2002, 2008, and 2014.

Alhambra is a city located in the western San Gabriel Valley region of Los Angeles County, California, United States, approximately eight miles from the Downtown Los Angeles civic center. It was incorporated on July 11, 1903. As of the 2020 census, the population was 82,868. The city's ZIP Codes are 91801 and 91803.