Market Street is a major thoroughfare in San Francisco, California. It begins at The Embarcadero in front of the Ferry Building at the northeastern edge of the city and runs southwest through downtown, passing the Civic Center and the Castro District, to the intersection with Portola Drive in the Twin Peaks neighborhood. Beyond this point, the roadway continues into the southwestern quadrant of San Francisco. Portola Drive extends south to the intersection of St. Francis Boulevard and Sloat Boulevard, where it continues as Junipero Serra Boulevard.

Junipero Serra Boulevard is a major boulevard in and south of San Francisco named after Franciscan friar Junipero Serra. Within the city, it forms part of the route of State Route 1, the shortest connection between Interstate 280 and the Golden Gate Bridge. The remainder, in San Mateo County, was bypassed or replaced by I-280, the Junipero Serra Freeway. The boulevard was one of several new roads built along the San Francisco Peninsula before the age of freeways, and became a state highway known as Route 237 in 1956, receiving the State Route 117 designation in the 1964 renumbering, only to be deleted from the state highway system the next year. Two other regional highways—Bayshore Highway and Skyline Boulevard—were also upgraded into or bypassed by freeways.