Marta Sahagún (Spanish pronunciation: [ˈmaɾta sa ˈɣun]; born Marta María Sahagún Jiménez served as the First Lady of Mexico from 2 July 2001, when she married President Vicente Fox, until he left office on 30 November 2006. Her tenure was marked by her outspoken views and active role in her husband's administration, in contrast to previous First Ladies of Mexico, as well as several controversies regarding her nonprofit Vamos México foundation and her family's business dealings.

First Lady of Mexico, also known as First Lady of the United Mexican States, is the unofficial title of the wife of the president of Mexico. Beatriz Gutiérrez Müller is the wife of current president Andrés Manuel López Obrador.