Mary Jane "MJ" Watson is a fictional character in Sam Raimi's Spider-Man film series. Based on the character of the same name, she is portrayed by Kirsten Dunst. In the films, Mary Jane is Peter Parker's next-door neighbor, childhood crush, and primary love interest. Though Mary Jane dates several other men in the first two films, she ultimately falls in love with Peter and Spider-Man and discovers they are one and the same. Despite his strong feelings for her, Peter initially declines a relationship with her in order to keep her safe, but they eventually become a couple in the end.

Spider-Man in film dates back to 1977, the rights belonging to Marvel until 1999, when Sony bought them for $7 million. He has been Marvel's most successful character in the cinema industry ever since. After selling the Spider-Man motion picture rights to Sony, Marvel eventually founded its own studio, developing the Marvel Cinematic Universe (MCU) based on the characters they still held the rights to. This would change in 2016, when Sony and Disney entered an agreement to include Spider-Man in the MCU. Despite some disagreements pertaining to finances and merchandising between the two parties, the agreement proved a successful endeavor for both companies. The following two Avengers sequels, finally with Spider-Man, crossed the $2 billion mark at worldwide box office for the first time. Meanwhile, Sony in association with Marvel launched the Sony's Spider-Man Universe (SSU), with Sony entering a 3 billion-dollar streaming agreement with Netflix and Disney.