Maryborough railway station is located on the Mildura line in Victoria, Australia. It serves the town of Maryborough, and it opened on 7 July 1874.

The Mildura railway line is a heavy rail line in northwestern Victoria, Australia. The line runs from Yelta station to Ballarat station via the settlements of Mildura, Ouyen and Maryborough in an approximate south-southeasterly direction. Initial sections of the line opened from Ballarat in 1874 and the line reached Mildura in 1903.