Maryland Route 304 is a state highway in the U.S. state of Maryland. The highway runs 15.23 miles (24.51 km) from Spider Web Road near Centreville east to MD 312 in Bridgetown. MD 304 connects Centreville with U.S. Route 301 and several small settlements in central Queen Anne's County and northern Caroline County, including Ruthsburg and Bridgetown. The first sections of modern MD 304 were improved in the 1910s, but much of the highway from Centreville to Ruthsburg was constructed from the mid-1930s to the early 1940s. The part of the highway west of Centreville was constructed as Maryland Route 606 and became part of MD 304 in 1950. Since the 1950s, the highway through Centreville has been municipally maintained. MD 304 was extended east to MD 405 and replaced that route to Bridgetown in the 1960s. The US 301 junction became a superstreet intersection in 2011 and a double-roundabout partial cloverleaf interchange in 2017.

Centreville is an incorporated town in Queen Anne's County, Maryland, United States on the Delmarva Peninsula. Incorporated in 1794, it is the county seat of Queen Anne's County. The population was 4,285 at the 2010 census. The ZIP code is 21617 and the area codes are 410 and 443. The primary local telephone exchange is 758. It hosts the Queen Anne's County Fair each summer and was home to three franchises during the existence of the Eastern Shore Baseball League—the Colts, Red Sox, and Orioles.